How to say one has to do one's best in anything. in Japanese

1)何事何事(nanigoto) (n) what/something/everything/nothing/something or other/unspecified matterにもにも(nimo) (exp) also/too/not ... either/as well/even最善最善(saizen) (n) the very bestを(wo) (prt) indicates direct object of action/indicates subject of causative expression/indicates an area traversed/indicates time over which action takes place/indicates point of departure or separation of action/indicates object of desire, like, hate,尽くさno dictionary result, likely a conjigated verbno dictionary result, likely a conjigated verbなければならないなければならない(nakerebanaranai) (exp) have to do/must/should/ought to。(。) Japanese period "."    
nanigoto nimo saizen wo tsukusa nakerebanaranai 。
Grammer form日常会話 (Casual form)Casual form (nichijoukaiwa)
everyday casual language, commonly used between friends and family.
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