How to say i hope this medicine works. in Esperanto

1)Mi esperas, ke tiu kuracilo efikas.    
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Translation by al_ex_an_der
2)Mi esperas, ke tiu sanigilo efikas.    
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Translation by al_ex_an_der
3)Mi esperas, ke tiu medikamento efikas.    
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Translation by al_ex_an_der
4)Mi esperas, ke tiu medicinaĵo efikas.    
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