How to say his illness defeated all his hopes. in Japanese

1)病気病気(byouki) (n,adj-no) illness/disease/sicknessの(no) (prt) indicates possessive/nominalizes verbs and adjectives/substitutes for "ga" in subordinate phrases/indicates a confident conclusion/ indicates emotional emphasis/indicates questionためにために(tameni) for sake of/on behalf of/as a result of彼の彼の(kano) (adj-pn) that希望希望(kibou) (n,vs) hope/wish/aspirationは(ha) (int) indicating a subject/yes/indeed/well/ha!/what?/huh?/sighすべてすべて(subete) (adj-no,n-adv,n) all/the whole/entirely/in general/wholly/overall挫折挫折(zasetsu) (n,vs) setback/failure/frustration/discouragementしたした(shita) (n) did/a past form of the previous verb/tongue/tongue-like object/clapper/talon。(。) Japanese period "."    
byouki notameni kano kibou hasubete zasetsu shita 。
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Other sentences with translations
sudden misfortune deprived her of her reason.

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that'll make for a memorable time.

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he sent me a brief letter.

i can't make head nor tail of it.

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