How to say it was the biggest mistake of my life. in Japanese

1)生涯no dictionary result, likely a conjigated verbno dictionary result, likely a conjigated verbで(de) (prt) indicates location of action/at/in/indicates time of action/indicates means of action/cause of effect/by/and then/so/indicates continuing action/ indicates certainty, emphasis, etc.一番一番(ichiban) (n-adv) best/first/number one/game/round/bout/fall/eventの(no) (prt) indicates possessive/nominalizes verbs and adjectives/substitutes for "ga" in subordinate phrases/indicates a confident conclusion/ indicates emotional emphasis/indicates question間違い間違い(machigai) (n) mistake/error/blunder/accident/mishap/trouble/improper conduct/indiscretionですです(desu) (aux) be/is/are。(。) Japanese period "."    
shougai de ichiban no machigai desu 。
Grammer form丁寧語 (Polite form)Polite form (teineigo)
convays a sense of politeness, used when speaking to strangers, people older than you, higher social status ect.
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