How to say smoking has a great deal to do with cancer. in Japanese

1)喫煙喫煙(kitsuen) (n,vs) smokingは(ha) (int) indicating a subject/yes/indeed/well/ha!/what?/huh?/sigh癌(gan) (n) cancerと(to) (prt,conj) if/when/and/with/particle used for quoting/quoting particle/ promoted pawn/ indicates question大い大い(ooi) (pref) greater/upper/senior/a great deal/very muchに(ni) (prt) indicates such things as location of person or thing, location of short-term action, etc.関係関係(kankei) (n,vs,adj-no) relation/relationship/connection/participation/involvement/concern/influence/effect/sexual relations/sexual relationship/related to .../connected to ...が(ga) (prt) indicates sentence subject/indicates possessive/but/however/still/andあるある(aru) (adj-pn) a certain .../some ...。(。) Japanese period "."    
kitsuen ha gan to ooi ni kankei gaaru 。
Grammer form日常会話 (Casual form)Casual form (nichijoukaiwa)
everyday casual language, commonly used between friends and family.
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