How to say some diseases are caused by a defective gene. in Japanese

1)一部一部(ichibu) (n-adv,n) one part/one portion/one section/some/one copyの(no) (prt) indicates possessive/nominalizes verbs and adjectives/substitutes for "ga" in subordinate phrases/indicates a confident conclusion/ indicates emotional emphasis/indicates question疾患疾患(shikkan) (n,adj-no) disease/ailment/illnessの(no) (prt) indicates possessive/nominalizes verbs and adjectives/substitutes for "ga" in subordinate phrases/indicates a confident conclusion/ indicates emotional emphasis/indicates question原因原因(gen in) (n,vs) cause/origin/sourceは(ha) (int) indicating a subject/yes/indeed/well/ha!/what?/huh?/sigh欠陥欠陥(kekkan) (n) defect/fault/deficiency/deformity/shortage/gap遺伝子遺伝子(idenshi) (n) gene/geneticですです(desu) (aux) be/is/are。(。) Japanese period "."    
ichibu no shikkan no gen in ha kekkan idenshi desu 。
Grammer form丁寧語 (Polite form)Polite form (teineigo)
convays a sense of politeness, used when speaking to strangers, people older than you, higher social status ect.
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Translation by adlnbvrtn
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