How to say i can't handle it in Japanese

1)我慢我慢(gaman) (n,vs) patience/endurance/perseverance/tolerance/self-control/self-denialで(de) (prt) indicates location of action/at/in/indicates time of action/indicates means of action/cause of effect/by/and then/so/indicates continuing action/ indicates certainty, emphasis, etc.きないよno dictionary result, likely a conjigated verbno dictionary result, likely a conjigated verb    
gaman dekinaiyo
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