How to say he failed in his business in spite of his efforts. in Japanese

1)彼(kare) (ok) that , or something understood without naming it directly)/that person/over there/hey/eh?/thatは(ha) (int) indicating a subject/yes/indeed/well/ha!/what?/huh?/sigh努力努力(doryoku) (n,vs) great effort/exertion/endeavour/endeavor/effortを(wo) (prt) indicates direct object of action/indicates subject of causative expression/indicates an area traversed/indicates time over which action takes place/indicates point of departure or separation of action/indicates object of desire, like, hate,し(shi) (num) 10^24/septillion/quadrillionたにもno dictionary result, likely a conjigated verbno dictionary result, likely a conjigated verb関(kan) (n,n-suf) barrier/gateわ(wa) (prt) indicates emotion or admiration/adds a female middle aged feel at the end of a sentenceらずno dictionary result, likely a conjigated verbno dictionary result, likely a conjigated verb、(、) Japanese comma事業事業(jigyou) (n) project/enterprise/business/industry/operations/act/deed/conductに(ni) (prt) indicates such things as location of person or thing, location of short-term action, etc.失敗失敗(shippai) (n,adj-no,vs) failure/mistake/blunderしたした(shita) (n) did/a past form of the previous verb/tongue/tongue-like object/clapper/talon。(。) Japanese period "."    
kareha doryoku woshitanimo kakawa razu 、 jigyou ni shippai shita 。
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Other sentences with translations
she took a lot of baggage with her.

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i had a heart attack.

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i have lost all my money.

you are good to help me.

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